Medicine changes lives.
Research changes the world.
Every day, Mass General Brigham scientists chart new terrain in biomedical research to prevent and treat human disease and advance patient care — locally and across the globe.
Recent News
Looking for Insights into Mucolipidosis IV
Amanda Furness, PhD Amanda Furness, PhD, is a postdoctoral research fellow in the Center for Genomic Medicine at Massachusetts General Hospital. Her poster, Therapeutic insight into Mucolipidosis IV via in vitro glia models, recently won an award at Mass General’s Research Fellow Poster Celebration. We asked Dr. Furness about her research: What problem(s) are you
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Celebrating Mass General’s Remarkable Research Staff
Both sides of the Bulfinch Tents at Massachusetts General Hospital were bustling May 24 at the annual Research Staff Appreciation Day event. More than 2,000 research staff members – including lab technicians, research coordinators and technologists – were invited to enjoy a picnic-style lunch, ice cream and raffles for tickets to the Museum of Science. Bowls
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New Imaging Protocol Could Vastly Accelerate Clinical Trials for New ALS Treatments
Researchers at Massachusetts General Hospital have developed a new technique for imaging the brains of patients with amyotrophic lateral sclerosis (ALS) that could vastly reduce the cost and time needed for new clinical trials—while also improving the accuracy of test results.
New National Research Program Focuses on Connection and Community
Why do some individuals and populations experience poorer health outcomes than others? When it comes to health disparities in the United States, many would say the problem is a vicious cycle. Research shows that diseases like heart disease and cancer disproportionately affect racial and ethnic minority populations. Yet biomedical research studies and clinical trials have
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How New Biomarkers and Smartphone Apps Could Provide New Hope for ALS Patients
James Berry, a researcher in the Neurological Clinical Research Institute at Massachusetts General Hospital, is working to build tools and identify biomarkers to improve clinical trial methodology. His goal is to speed up the process of identifying the next drug that will slow, reverse or even prevent ALS in the future
Can Studying a Rare Inherited Form of ALS Lead to Earlier Diagnosis and New Treatments?
Katharine Nicholson, MD Hereditary forms of amyotrophic lateral sclerosis (ALS) may only account for 10 percent of all ALS cases, but the insights that researchers gain from studying this small population may be the key to unlocking new treatments for this devastating disease. That’s the hope of Katharine Nicholson, MD, a physician-investigator at the Neurological
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A Newly Discovered Link Between Gut Bacteria and Cholera
45654786 – close up 3d illustration of microscopic cholera bacteria infection Researchers from Massachusetts General Hospital, Duke University and the International Centre for Diarrheal Disease Research in Dhaka, Bangladesh, have used machine learning algorithms to find patterns within communities of bacteria living in the human gut. These patterns could indicate who among the approximately one
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Online Platform Accelerates Rare Disease Research
Earlier this week, the Mass General Neurological Clinical Research Center (NCRI)’s NeuroBANK™ won Bio-IT World‘s Best Practice award in the Personalized & Translational Medicine category. What is the NeuroBANK, and how is it helping to accelerate the discovery, development, and delivery of future treatments for rare diseases including amyotrophic lateral sclerosis (ALS)? Filling a Need
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Paganoni Advances ALS Research and Care with Technology
Sabrina Paganoni, MD, PhD Technological advancements have revolutionized nearly every field of medicine from orthopedics to genetic testing. Sabrina Paganoni, MD, PhD, a clinician and researcher in the Neurological Clinical Research Institute (NCRI) at Massachusetts General Hospital, has seen firsthand the potential power and impact technology could have for amyotrophic lateral sclerosis (ALS). Paganoni is
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Research Finds Daily Exercise Can Make for Healthier, Younger Hearts
Researchers have identified a cellular level link between exercise and healthy hearts that strengthens the case for physical activity.