Medicine changes lives.
Research changes the world.
Every day, Mass General Brigham scientists chart new terrain in biomedical research to prevent and treat human disease and advance patient care — locally and across the globe.
Recent News
Can Studying a Rare Inherited Form of ALS Lead to Earlier Diagnosis and New Treatments?
Katharine Nicholson, MD Hereditary forms of amyotrophic lateral sclerosis (ALS) may only account for 10 percent of all ALS cases, but the insights that researchers gain from studying this small population may be the key to unlocking new treatments for this devastating disease. That’s the hope of Katharine Nicholson, MD, a physician-investigator at the Neurological
Read more
A Newly Discovered Link Between Gut Bacteria and Cholera
45654786 – close up 3d illustration of microscopic cholera bacteria infection Researchers from Massachusetts General Hospital, Duke University and the International Centre for Diarrheal Disease Research in Dhaka, Bangladesh, have used machine learning algorithms to find patterns within communities of bacteria living in the human gut. These patterns could indicate who among the approximately one
Read more
Online Platform Accelerates Rare Disease Research
Earlier this week, the Mass General Neurological Clinical Research Center (NCRI)’s NeuroBANK™ won Bio-IT World‘s Best Practice award in the Personalized & Translational Medicine category. What is the NeuroBANK, and how is it helping to accelerate the discovery, development, and delivery of future treatments for rare diseases including amyotrophic lateral sclerosis (ALS)? Filling a Need
Read more
Paganoni Advances ALS Research and Care with Technology
Sabrina Paganoni, MD, PhD Technological advancements have revolutionized nearly every field of medicine from orthopedics to genetic testing. Sabrina Paganoni, MD, PhD, a clinician and researcher in the Neurological Clinical Research Institute (NCRI) at Massachusetts General Hospital, has seen firsthand the potential power and impact technology could have for amyotrophic lateral sclerosis (ALS). Paganoni is
Read more
Research Finds Daily Exercise Can Make for Healthier, Younger Hearts
Researchers have identified a cellular level link between exercise and healthy hearts that strengthens the case for physical activity.
Mass General Investigators on the Cutting Edge of ALS Research
Neurological Clinical Research Institute team May is ALS Awareness Month, intended as a time to raise awareness of and foster research for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Eventually these motor neurons die, effecting a
Read more
Racing to Stop a ‘Silent’ Killer
The ability to detect ovarian cancer in its early stages continues to elude researchers. Cheng Wang, PhD, is determined to change that.
Mass General Researcher Maps the Connections Between Allergies and the Microbiome
Nitya Jain, PhD, a researcher at the MassGeneral Hospital for Children’s Mucosal Immunology and Biology Research Center, is studying how changes in the bacterial population in the gut influence T cell development and how signals between the two systems drive this process.
Study Looks at Risk Factors for Overdose in Adolescents
A team of investigators from the Addiction Recovery Management Service at Massachusetts General Hospital have identified factors that may increase the risk of drug overdose in adolescents and young adults. The results of their study were published in the Journal of Clinical Psychiatry last month. Here’s a short video summarizing their findings: “Very little
Read more
Large-Scale Study Provides New Insights Into the Genetic Contributors to Schizophrenia
Tarjinder Singh, PhD, is a postdoctoral fellow in the lab of Mark Daly, PhD, in the Analytic and Translational Genetics Unit at Massachusetts General Hospital. His poster, The meta-analysis of rare coding variants in the whole-exome sequences of 25,000 cases and 50,000 controls implicates individual risk genes for schizophrenia, was among the winners at this
Read more