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Mass General Brigham Research Wrapped for 2025

By Nicoletta Valenzano, MPH | Research Wrapped | 0 comment | 9 December, 2025 | 1

Mass General Brigham's

Research Wrapped for 2025

At Mass General Brigham in 2025, our researchers continued to work collaboratively to better understand the causes of disease and develop new strategies for diagnosis, treatment and prevention.

As always, our researchers wowed us with their ingenuity, creativity and productivity.

Here are some of the highlights from the year in research:

By the Numbers

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75+ Highly Cited Researchers

Clarivate Analytics’ Web of Science Group compiles an annual list of scientists around the globe who have demonstrated significant influence through publication of multiple highly cited papers that rank in the top 1% by citations for field and year.

In 2025, we were pleased to announce that over 75 Mass General Brigham investigators made the list.

paper

21,000+ Published Research Papers

Every single day at Mass General Brigham, new papers are being published by our researchers, moving their respective fields forward.

In 2025, our researchers were among the authors on over 21,000 scientific papers.

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$2.73 Billion in Research Operations

In 2025, the total research operations at Mass General Brigham totaled $2.73 billion.

This is a credit to the hard work and groundbreaking science of our investigators, who are supported by crucial grants from the federal government, as well as foundations, industry partners, venture capital, philanthropy and other sources.

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10,235 Grant Proposals

Our researchers are always looking forward to the next big discoveries in science and medicine. This year, Mass General Brigham researchers wrote and submitted 10,235 grant proposals seeking to secure funding for new research projects.

5

185 Research Press Releases

Each year, our communications team works closely with our researchers to write and distribute press releases and research spotlights to share new research findings with the world. This year, we published 185 press releases with an average Altmetric score of 322. We also published 90 Research Spotlights in 2025.

2

554,205 Visits to our Clinical Trials Website

In 2025, over half a million people visited Rally, the Mass General Brigham clinical trials website, and over 76,000 individuals applied to be part of a clinical trial.

The most popular studies searched for in 2025 included those seeking to learn more about new medications and imaging techniques, yoga and alternative therapies and appetite and healthy aging.

 

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673 Patents

Research at Mass General Brigham often leads to new discoveries and inventions that could one day be translated into new treatments for patients.

The first step in the process is to patent new discoveries.

In the 2025 fiscal year, Mass General Brigham researchers filed 1,634 applications for the protection of intellectual property and received 673 patents so far.

“In the face of disruptive forces that shook the foundation of biomedical research in 2025, the hard work, dedication and perseverance of our investigators preserved our research mission at MGB. Discoveries made by the MGB research community will impact the lives of our patients now and in the future.”
Paul Anderson, MD, PhD
Chief Academic Officer
Mass General Brigham

Research in the News

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In a large study which followed the dietary choices of more than 200,000 people over 30 years that was led by Yu Zhang, MBBS, the researchers found that more plant oils and less butter could lead to better health. Read more on CNN Health. 

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Mass General Brigham researchers develop and study an at-home smell test for early detection of Alzheimer’s disease. Read the New York Post article. 

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A study led by researchers at Mass General Brigham suggests that when it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing. Read the Food & Wine article. 

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Our researchers looked at data from more than 150,000 people who were followed for at least three decades. They found that people who regularly ate two or more servings of yogurt a week had lower rates of certain types of colorectal cancer. Read more on NPR.

The Year in Research Photos

Battistone lab team
Picture from left to right are Battistone lab members Angela Chen, BS, Micah C. Purba, BA, Maria Agustina Battistone, PhD, Maria Carolina Avenatti, MD, and Isinsu Bastepe, BS.
Panelists at the 2025 World Medical Innovation Forum
Panelists at the 2025 World Medical Innovation Forum
Chris Coburn, Robert Kingston, Jeannie Lee and Kathryn Rexode on stage at the 2025 World Medical Innovation Forum in Boston
World Medical Innovation Forum First Look Winners
Nouchine Hadjikhani, MD, PhD, with Nicole Zürcher, PhD. Zürcher was a PhD student of Hadjikhani’s in Switzerland and is now an investigator at the Martinos Center, where both researchers are frequent collaborators.
Nouchine Hadjikhani, MD, PhD, with Nicole Zürcher, PhD. Zürcher was a PhD student of Hadjikhani’s in Switzerland and is now an investigator at the Martinos Center, where both researchers are frequent collaborators.
MGB leaders visited the Massachusetts State House this fall to discuss the importance of funding for research.
MGB leaders visited the Massachusetts State House this fall to discuss the importance of funding for research.
The Indzhykulian Lab at Mass Eye and Ear
The Indzhykulian Lab at Mass Eye and Ear
Brigham and Women's Summer Research Program members
Brigham and Women's Summer Research Program members
Students at the Summer Research Trainee Program orientation day in the Ether Dome.
Students at the Summer Research Trainee Program orientation day in the Ether Dome.
Pictured, from left to right, are Sokol lab members Peri Matatia, Elena Christian, Cai Han, Doremi (Xinyi) Feng and Caroline Sokol, MD, PhD.
from left to right: Peri Matatia, Elena Christian, Cai Han, Doremi (Xinyi) Feng, Caroline Sokol
Tarun Lab members, from left to right, include Steven Cicero, Nicolas Horan, Singhal Tarun, MD, MBSS, and Marylin Collazo.
Tarun Lab members Steven Cicero, Nicolas Horan, Singhal Tarun, MD, MBSS, and Marylin Collazo.
Members of the Anderson Lab at work.
Members of the Anderson Lab at work.
A photo collage from the American Society of Clinical Oncology meeting.
A photo collage from the American Society of Clinical Oncology meeting.
The ceremony for the Claflin Distinguished Scholar Awards.
The ceremony for the Claflin Distinguished Scholar Awards.
Mass General Brigham researchers on the big screen in Times Square,, New York City
Mass General Brigham researchers on the big screen in Times Square,, New York City
Dr. Robert Green giving a TED Talk on genetic screening in newborns.
Dr. Robert Green giving a TED Talk on genetic screening in newborns.
Members of the Edlow Lab post in front of their winning poster from the 2025 Celebration of Science.
Members of the Edlow Lab post in front of their winning poster from the 2025 Celebration of Science.
Dr. Nina Gold and her team.
Dr. Nina Gold and her team.
Dr. Mike Talkowski receiving an award at the 2025 American Society for Human Genetics Meeting.
Dr. Mike Talkowski receiving an award at the 2025 American Society for Human Genetics Meeting.
The Martinos Center summer students.
The Martinos Center summer students.
Jodi Gilman, PhD, and her team.
Jodi Gilman, PhD, and her team.
Members of the FARIL Lab.
Members of the FARIL Lab.
Mass General Brigham Down Syndrome researchers at the 2025 National Down Syndrome Conference.
Mass General Brigham Down Syndrome researchers at the 2025 National Down Syndrome Conference.
Members of the Center for Surgery and Public Health.
Members of the Center for Surgery and Public Health.

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From left to right are Karl's son-in-law Perry, daughter Lily (married to Perry), son Ben, wife Lucy, and Karl Helfrich.

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Remembering Dr. Joel Habener

An image of a concerned woman looking at her phone.

Learning More About How Parents Respond to Digital Alerts of Potential Child Suicide Risk

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