Mass General Brigham Research Wrapped for 2025

Mass General Brigham's

Research Wrapped for 2025

At Mass General Brigham in 2025, our researchers continued to work collaboratively to better understand the causes of disease and develop new strategies for diagnosis, treatment and prevention.

As always, our researchers wowed us with their ingenuity, creativity and productivity.

Here are some of the highlights from the year in research:

By the Numbers

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75+ Highly Cited Researchers

Clarivate Analytics’ Web of Science Group compiles an annual list of scientists around the globe who have demonstrated significant influence through publication of multiple highly cited papers that rank in the top 1% by citations for field and year.

In 2025, we were pleased to announce that over 75 Mass General Brigham investigators made the list.

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21,000+ Published Research Papers

Every single day at Mass General Brigham, new papers are being published by our researchers, moving their respective fields forward.

In 2025, our researchers were among the authors on over 21,000 scientific papers.

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$2.73 Billion in Research Operations

In 2025, the total research operations at Mass General Brigham totaled $2.73 billion.

This is a credit to the hard work and groundbreaking science of our investigators, who are supported by crucial grants from the federal government, as well as foundations, industry partners, venture capital, philanthropy and other sources.

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10,235 Grant Proposals

Our researchers are always looking forward to the next big discoveries in science and medicine. This year, Mass General Brigham researchers wrote and submitted 10,235 grant proposals seeking to secure funding for new research projects.

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185 Research Press Releases

Each year, our communications team works closely with our researchers to write and distribute press releases and research spotlights to share new research findings with the world. This year, we published 185 press releases with an average Altmetric score of 322. We also published 90 Research Spotlights in 2025.

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554,205 Visits to our Clinical Trials Website

In 2025, over half a million people visited Rally, the Mass General Brigham clinical trials website, and over 76,000 individuals applied to be part of a clinical trial.

The most popular studies searched for in 2025 included those seeking to learn more about new medications and imaging techniques, yoga and alternative therapies and appetite and healthy aging.

 

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673 Patents

Research at Mass General Brigham often leads to new discoveries and inventions that could one day be translated into new treatments for patients.

The first step in the process is to patent new discoveries.

In the 2025 fiscal year, Mass General Brigham researchers filed 1,634 applications for the protection of intellectual property and received 673 patents so far.

“In the face of disruptive forces that shook the foundation of biomedical research in 2025, the hard work, dedication and perseverance of our investigators preserved our research mission at MGB. Discoveries made by the MGB research community will impact the lives of our patients now and in the future.”
Paul Anderson, MD, PhD
Chief Academic Officer
Mass General Brigham

Research in the News

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In a large study which followed the dietary choices of more than 200,000 people over 30 years that was led by Yu Zhang, MBBS, the researchers found that more plant oils and less butter could lead to better health. Read more on CNN Health. 

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Mass General Brigham researchers develop and study an at-home smell test for early detection of Alzheimer’s disease. Read the New York Post article. 

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A study led by researchers at Mass General Brigham suggests that when it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing. Read the Food & Wine article. 

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Our researchers looked at data from more than 150,000 people who were followed for at least three decades. They found that people who regularly ate two or more servings of yogurt a week had lower rates of certain types of colorectal cancer. Read more on NPR.

The Year in Research Photos

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