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We have chosen to postpone several of our upcoming events to keep our friends and neighbors safe, but be sure to check back in for updates. We hope to see you all and share some awesome science with you soon!

-Your friends at the Mass General Research Institute

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mgbresearch

Medicine changes lives, research changes the world. @massgeneralbrigham

This #Nurses Week, we’re celebrating the nurses This #Nurses Week, we’re celebrating the nurses whose dedication goes beyond the bedside. 

For nearly 50 years, over 280,000 nurses have contributed to the groundbreaking Nurses’ Health Study, shaping what we know about how lifestyle, medications, and mental health influence chronic disease. 

Their impact on public health is immeasurable, and the research is still going strong today. 

Read more at the link in our bio. 

#NursesWeek #NursesHealthStudy #WomensHealth #PublicHealthResearch
This #NursesWeek, we honor a pioneer in nursing: A This #NursesWeek, we honor a pioneer in nursing: Ada Plumer, RN. 💉🩺

In 1940, Ada became the first IV nurse at @massgeneral. What started with her answering 300 calls for IV therapy in her first year would grow into a specialized field that changed nursing forever.

Ada developed the hospital’s first IV team, co-founded what is now the Infusion Nurses Society, and wrote the book on IV therapy, Principles and Practices of IV Therapy, still in use today.

Humble and dedicated, she mentored generations of nurses and continued to teach even after retirement.

Today, her legacy lives on in the 40+ nurses and 9 techs of our Vascular Access & PICC Program, who performed over 33,000 IV insertions in 2023 alone.

Thank you, Ada, and thank you to all nurses who follow in her footsteps. 

Read more at the link in our bio.

#MassGeneral #NursesWeek2025 #AdaPlumer #IVNursing #NursingHistory #MGHSON #InfusionTherapy #ThankANurse
Did you know there are 2,700+ clinical trials happ Did you know there are 2,700+ clinical trials happening right now across Mass General Brigham? 

From cancer to mental health to rare diseases, our researchers are pushing the boundaries of what’s possible in medicine. 

#massgeneral #medicalinnovation #patientcare #hospital
May the fourth be with you 💫 Did you know tha May the fourth be with you 💫 

Did you know that researchers from @massgeneralbrigham have created the world's smallest laser? At 170 nm wide, you could fit over 500 of these lasers within the width of a single strand of human hair. 

Sangyeon Cho, PhD, along with researchers from the Yun Lab at the Wellman Center for Photomedicine, have created the nanolasers to help in the fight against cancer. In the future, with their innovative methods, they hope to be able to use the lasers to track individual cancer cells' movements over a period of time. 

Read more about their research at the link in our bio.
The Goldstein Lab at @massgeneral and Mass General The Goldstein Lab at @massgeneral and Mass General Hospital for Children studies how the "second brain" in our gut, called the enteric nervous system, develops and functions. This network of nerves helps keep everything in our digestive system moving smoothly.

By better understanding how it works, the team hopes to discover new treatments for children and adults with gut disorders linked to nerve problems.

#GutHealth #Neuroscience #PediatricResearch #MassGeneral #DigestiveHealth
Could a probiotic help lower HIV risk? New researc Could a probiotic help lower HIV risk? New research suggests it might.

A new study led by researchers from @mghobgyn and colleagues in South Africa tested a vaginal probiotic called LACTIN-V, which contains Lactobacillus crispatus, a “good” bacteria that helps protect against infections. The probiotic was tested in young South African women who were at high risk for HIV.

After four weeks, women who used LACTIN-V were much more likely to have a healthier balance of vaginal bacteria compared to those who received a placebo. They also had fewer immune cells in the genital tract that are known to be targets for HIV infection. The probiotic was safe, easy to use, and well-liked by most participants.

These findings show that it may be possible to lower HIV risk by improving vaginal health with beneficial bacteria, especially important for young women in areas with high rates of HIV.

(Pictured: Caroline Mitchell, MD MPH, from @massgeneral, author on the study)
This week, many of our lead clinicians and researc This week, many of our lead clinicians and researchers attended the annual American Association for Cancer Research (AACR) conference, where the brightest minds in cancer care came together to share their insights and innovations with the world. 

Hear from Dave Ryan, MD, President of MGB Cancer Institute about how researchers from Mass General Brigham are helping leading charge. 

By staying at the forefront of cancer discovery, we're advancing science today to deliver tomorrow's excellence in cancer care.

#AACR25 #Cancercare #innovationincancer
Happy American Association for Cancer Research ann Happy American Association for Cancer Research annual conference week! 

Hear from Andy Chan, MD, MPH, about the research he presented at #AACR25. Dr. Chan is the Chair of the Clinical and Translational Epidemiology Unit and the Director of Cancer Epidemiology at @mghcancercenter.
🧬 Happy DNA Day! Ever wonder what makes you, 🧬 Happy DNA Day! 

Ever wonder what makes you, you?  In this video, Heidi Rehm, PhD, explains the crucial role DNA plays in our daily functions. 

Through her research, Dr. Rehm is identifying genes associated with rare diseases. Her work aims to provide families with answers, guide them towards appropriate treatments, and help them better plan for the future.
The medical and historical communities have teamed The medical and historical communities have teamed up to reveal the secrets behind the items we see on display in museums around the world! 

Using advanced dual-energy computed tomography (CT) devices, which are commonly used to scan patients, researchers scanned eight ceramic artifacts from Central and South America.

The scans revealed the intricate structures inside vessels thought to be used in rituals or buried with elites in ancient Peru. The CT scans showed how sounds are produced when liquid moves through the chambers inside these artifacts."
🏃‍♀️🏅A huge congratulations to all the 🏃‍♀️🏅A huge congratulations to all the incredible researchers who laced up and ran the Boston Marathon! Your dedication—both in the lab and on the course—inspires us all. 💙💛 

Whether you're pushing the frontiers of science or pushing through Heartbreak Hill, we're so proud to cheer you on.

#BostonMarathon #ResearchOnTheRun #MGBResearch #BostonStrong
Every Boston #marathon runner is motivated by some Every Boston #marathon runner is motivated by something, and Eline Laurent, who is running for the @brighamandwomens Stepping Strong Marathon Team, is no different.

"My first race was in kindergarten, where I showed up in sandals and a summer dress. Since then, I have never stopped running. Since middle school, my dream has been to one day run the Boston Marathon," said Laurent.

As a Clinical Research Coordinator with the Early Brain Development Initiative, her work is aimed at developing and implementing prenatal and early life interventions to prevent neuropsychiatric illnesses, particularly in children at increased risk for these disorders.

"Personally, I believe my work in research has made me a better runner, and marathon training has enhanced my focus and resilience in the lab," said Laurent.

As the Boston Marathon approaches, we’re spotlighting the inspiring individuals from the @massgeneralbrigham research community who will be running the race.

Read more of Eline's story at the link in our bio.
Curious what a week as a Postdoctoral Research Fel Curious what a week as a Postdoctoral Research Fellow at @MassGeneralBrigham looks like? We’ve got you covered! 

Follow Stephen and Annabel as they take you behind the scenes in their role as postdocs in the Kimberly Lab at Massachusetts General Hospital. The research team is dedicated to uncovering the underlying causes of secondary brain injury and translating these insights into diagnostic tools and innovative therapies.

Outside the lab, you’ll catch Stephen and Annabel staying active, getting their steps in, and enjoying Boston’s incredible food scene!

#NeuroResearch #Stroke #BostonLife
Every Boston #marathon runner is motivated by some Every Boston #marathon runner is motivated by something, and Hope Taft, Executive Director of @mghmartinos is no different. 

As the Boston Marathon approaches, we’re spotlighting the inspiring individuals from the @massgeneralbrigham research community who will be running the race.

"I love the idea of setting a goal, challenging myself daily through training and accomplishing something tangible at the end," said Taft. 

As Executive Director, Taft oversees day-to-day operations and strategy, including developing new partnerships and industry studies, and purchasing new capital equipment.

"There is a lot of ambiguity and uncertainty in research right now. Training has helped reinforce the importance of perseverance and balance," said Taft.

Read more of her story at the link in our bio. 

#bostonmarathon #running #research #runners
An Ode to Hidden Threads: Collagen Fibers | Submit An Ode to Hidden Threads: Collagen Fibers | Submitted by Maxwell Roth, MD

This image captures the intricate, fibrous structure of collagen, a key protein that gives strength and flexibility to our skin, bones, and tissues. By revealing its delicate, repeating patterns, this photo highlights collagen’s structural role as the body’s natural scaffold for growth and healing. 

Dr. Roth is a researcher in the Electron Microscopy Unit in the Department of Pathology at @massgeneral. 

Alongside the image, he submitted the following poem as well: 

A tapestry of silent strength, 
Binding bone to spirit, 
Flesh to memory. 
Holding us together in the tender bond of humanness. 
We are each a thread in this ancient loom, 
Stitched by unseen hands, 
Scaffolding of a deep lineage.

Pictured in the second photo: Maxwell Roth (left) and Martin Selig (right) at the MGRI Image Awards Gala, where Roth received the 2024 Golden Rosado Award for his image submission.
As a world-recognized leader in research, @massgen As a world-recognized leader in research, @massgeneralbrigham is home to the largest hospital-based research program in the U.S.

In 2024, over 80 of our researchers were named to the annual Highly Cited Researchers™ 2024 list from Clarivate. Each researcher selected has authored multiple studies that rank in the top 1% by citations for their field(s) and publication year over the past decade. 

“For our research to be truly impactful in improving healthcare, it has to reach beyond the walls of our institutions,” says Paul Anderson, MD, PhD, Chief Academic Officer of Mass General Brigham.
Every Boston #marathon runner is motivated by some Every Boston #marathon runner is motivated by something—whether it is personal athletic glory, raising funds to support a favorite charity, or just getting the chance to strut around Boston with a finishers’ medal and one of those cool striped jackets the day after the race.

As the Boston Marathon approaches, we’re spotlighting the inspiring individuals from the @massgeneralbrigham research community who will be running the race. 

Next up, we have Gabriel Alberts, who is running for Team Eye and Ear from @masseyeandear 

As a graduate research student, Gabriel works with Sunil Puria, PhD, studying how the cells inside our ears move around in order to help us hear.

#bostonmarathon #running #research #runners
OoSight | Submitted by Alana Mermin-Bunnell This OoSight | Submitted by Alana Mermin-Bunnell

This image shows egg cells (oocytes) from a mouse ovary, captured using a special technique called tissue clearing. By making the ovary transparent, researchers can see and count all the oocytes—shown here in pink—both in a single slice (left) and a 3D view (right).

Why does this matter? Alana Mermin-Bunnell at the PĂŠpin Lab at @massgeneral is using this technique to study fertility protection for children undergoing chemotherapy, helping to preserve their ability to have biological children in the future.
Every Boston marathon runner is motivated by somet Every Boston marathon runner is motivated by something—whether it is personal athletic glory, raising funds to support a favorite charity, or just getting the chance to strut around Boston with a finishers’ medal and one of those cool striped jackets the day after the race.

As the Boston Marathon approaches, we’re spotlighting the inspiring individuals from the Mass General Brigham research community who will be running the race this year. From clinical research coordinators to investigators and students, get to know the faces behind the bibs and the motivation behind running those (quite strenuous) 26.2 miles!

First up, we have Ashley Panzone from @brighamandwomens.
For more than two centuries, @massgenbrigham resea For more than two centuries, @massgenbrigham researchers have been shaping the future of medicine. From the first use of anesthesia to today’s cutting-edge advancements in #AI and gene therapy, our discoveries have transformed healthcare. 

Here’s to the past, present, and future of innovation across Mass General Brigham!
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